CleopatraRX

PearlPAK®

PearlPAK® is designed to treat cognitive decline during perimenopause and menopause and improves other common menopause symptoms such as hot flashes, poor sleep and vaginal dryness.

Each PearlPAK® includes:

  • 4 Weeks of treatment designed to mirror a woman’s cycle
  • Biodentical estriol (oral)
  • Biodentical progesterone (oral)

Recommended for:
Women in perimenopause and menopause (typically age 40-65) with an interest in keeping maintaining cognitive functions like memory, focus, and concentration. PearlPAK® also relieves common menopause symptoms such as hot flashes, vaginal dryness, and poor sleep.
PearlPAK® is an easy-to-swallow capsule taken twice per day.

Each monthly dose contains 28 days of a combination of estriol and and progesterone in a ratio designed to resemble a woman’s menstrual cycle. PearlPAK® is delivered in 3-month quantities.
Safety is our top priority. Every PearlPAK® patient must either be qualified by CleopatraRX™ medical staff or their own physician.

PearlPAK® was developed through decades of NIH funded research and has been clinically tested. Every PearlPAK® is formulated in partnership with nationally regulated pharmacies.

Made in the USA
PearlPAK® is designed for women in perimenopause and menopause who:

  • Have difficulty concentrating, remembering words, or are experiencing brain fog
  • Are experiencing hot flashes or night sweats
  • Have difficulty sleeping
Our formulation is simple:

  • Bioidentical estriol (oral)
  • Bioidentical progesterone (oral)

Patented delivery designed to mirror a woman’s natural cycle, delivering your treatment exactly as your body intended.

Smart Hormone Therapy

The only menopause treatment designed to improve cognition.

Supports memory and cognitive health issues caused by menopause

Estriol binds to different estrogen receptors as compared to standard HRT. By binding to a specific receptor in the brain, estriol offers brain protection.

Safe form of estrogen

Estriol has been safely used by menopausal women throughout Europe and Asia for decades. Progesterone in combination with estriol can be tailored to a low dose.

The PearlPAK® Advantage

PearlPAK®

Founded by a woman and a neurologist

Binds weakly to breast tissue

Improves cognitive function

Tailored dose specifically for you

other brands

Uses outdated forms of HRT

Binds strongly to breast tissue

Limited cognitive benefits

Patches, pellets & creams

FAQ

Questions & Answers

Find answers to your most frequently asked questions about this product below.
How do I know if I have brain fog?
If you are currently going through perimenopause or menopause, take our online survey to determine if you are experiencing the effects of brain fog. A CleopatraRX™ consulting nurse will review your survey to determine if PearlPAK® is right for you. We will notify you if you are not qualified, or schedule a consult with a physician if you are qualified. This process typically takes less than 24 hours.
Yes, in most cases. Brain fog can be diagnosed by a physician based on a patient self-reporting their symptoms and medical history. CleopatraRX™ consulting physicians use telemedicine technologies to diagnose cognitive dysfunction in the same way they diagnose patients in-person. The CleopatraRX™ consulting physician will ask a series of questions and use your answers to diagnose your condition and create a treatment plan using PearlPAK®, if appropriate. That’s why it’s vital you answer each question to the best of your knowledge and ensure that every communication with your physician is truthful, accurate, and thorough.
PearlPAK® was designed to help women with general brain fog caused by the effects of perimenopause and menopause. It is not intended for individuals with advanced cognitive and memory issues. If you suspect you may be suffering from a neurological condition such as dementia or Alzheimer’s, please contact your family physician.
Yes. CleopatraRX™ is the provider of PearlPAK®, and we work with a team of board certified and licensed physicians who operate under HIPAA compliance. HIPAA is a federal law that protects sensitive health information of patients. In addition, we have implemented strict security protocols and firewalls to protect your information.

PearlPAK® is Different from standard hormone replacement therapy (HRT).

PearlPAK® is offers neuroprotection and menopause relief with less binding affects to breast tissue typical of standard estradiol.

PearlPAK®’s
Unique Estrogen

The estrogen in PearlPAK® is estriol. Estriol binds to different estrogen receptors as compared to standard HRT. By binding to a specific receptor in the brain, estriol offers brain protection.

Decades of Safe Use Worldwide

Estriol is considered a safer form of estrogen. Estriol has been safely used by menopausal women throughout Europe and Asia for decades. Progesterone in combination with estriol can be tailored to a low dose.

Feel Better Through Menopause

Estriol in PearlPAK® reduces hot flashes, improves sleep, and improves vaginal dryness, while also addressing cognitive issues experienced in menopause.

Prevention is Key

Cognitive difficulties at menopause and brain atrophy in the hippocampus occurs with gradual worsening during years of being without estrogen. Called the “timing hypothesis”, the benefits of estrogen are greater with earlier treatment. The key is to be proactive, not reactive when it comes to brain health.