September 28, 2023, Published on eurekalert.org
A new study led by UCLA neurologist Dr. Rhonda Voskuhl sheds light on the underlying mechanisms linking menopause to cognitive deficits and brain atrophy, revealing a crucial role for estrogen receptor beta (ERĪ²) in astrocytes. The study, conducted on female mice, identified the specific brain regions and mechanisms responsible for the cognitive changes experienced during menopause.