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A Recipe for Remyelination

Published January 16th, 2024 in DDN

Molecules that promote restoration of the neuron’s myelin sheath could offer a reparative therapy for multiple sclerosis.

In a groundbreaking exploration led by Dr. Rhonda Voskuhl, PearlPAK inventor and a leading neurologist at UCLA, estriol, a hormone peaking in the third trimester of pregnancy, has emerged as a promising treatment for multiple sclerosis (MS). Inspired by the protective effect of pregnancy against MS, Dr. Voskuhl’s team demonstrated estriol’s anti-inflammatory and neuroprotective effects through clinical trials and recent mouse model studies. Their findings suggest estriol’s potential in inducing remyelination, offering hope for innovative neuroprotective treatments in MS.

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